Microarrays Research Today is a free monthly online journal that collates and summarizes the latest research about Microarrays, including details on experiments, designs, statistics, analysis, software.

SNPTools: a software tool for visualization and analysis of microarray data.

Sørensen FJ, Andersen CL, Wiuf C

Bioinformatics Research Center, University of Aarhus, Høegh Guldbergs Gade 10, Aarhus C, Denmark.

SUMMARY: We have created a software tool, SNPTools, for analysis and visualization of microarray data, mainly SNP array data. The software can analyse and find differences in intensity levels between groups of arrays and identify segments of SNPs (genes, clones), where the intensity levels differ significantly between the groups. In addition, SNPTools can show jointly loss-of-heterozygosity (LOH) data (derived from genotypes) and intensity data for paired samples of tumour and normal arrays. The output graphs can be manipulated in various ways to modify and adjust the layout. A wizard allows options and parameters to be changed easily and graphs replotted. All output can be saved in various formats, and also re-opened in SNPTools for further analysis. For explorative use, SNPTools allows various genome information to be loaded onto the graphs. AVAILABILITY: The software, example data sets and tutorials are freely available from http://www.birc.au.dk/snptools

Published 9 July 2007 in Bioinformatics, 23(12): 1550-2.
Full-text of this article is available online (may require subscription).

© 2004-2008 Microarrays Research Today. All Rights Reserved.